N,n'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process...

Details N,n'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process... N,n'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine, process...

C - Chemistry, Metallurgy

07

D

260/100, 260/110

C07D 241/08 (2006.01) C07D 499/00 (2006.01) C07D 499/70 (2006.01) C07D 501/36 (2006.01)

Patent

CA 1338624

A new compound called N,N'-carbonyl-bis-(4-ethyl- 2,3-dioxo)-piperazine of Formula I Image (I) A process for the preparation thereof based on the reaction of 4-ethyl-2,3-dioxo-piperazine or a trimethyl- silyl derivative thereof with carbonyl chloride or a derivative thereof. The use of the compound of Formula I as an intermediate in the preparation of compounds of Formula II Image (II) where R is a radical, substituted in alpha position, of a molecule of an acid selected from the group formed by phenylacetic acid, p-hydroxy phenylacetic acid, a 6- (phenylacetamido)-penicillanic acid and a 7-(phenyl- acetamido)-cephalosporanic acid.

582522

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