N,n'-diphenylurea derivatives suitable as kinase inhibitors

Details N,n'-diphenylurea derivatives suitable as kinase inhibitors N,n'-diphenylurea derivatives suitable as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2586929

Compounds of formula (I), wherein R1,R3 and X have the meanings cited in Claim 1, are inhibitors of tyrosinkinases, particularly TIE-2, and can be used to treat tumors.

L'invention concerne des composés de formule (I) dans laquelle R1, R3 et X ont les significations indiquées dans la revendication 1. Ces composés sont des inhibiteurs des tyrosine kinases, notamment de TIE-2, et des raf kinases et peuvent être utilisés, entre autres, pour le traitement de tumeurs.

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