N,n'-diphenylurea derivatives which are suitable as kinase...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2584179

The invention relates to compounds of formula (I), wherein R1a -R1e, R2a, R2b, R3 and R5 are as defined in the first claim. Said compounds are tyrosine- kinase inhibitors, in particular TIE-2 and Raf kinases which can be used, in particular for treating malignant tumors.

L'invention concerne des composés de formule (I) dans laquelle R<sup

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