N, n-disubstituted alkenamides and phenylalkenamides,...

Details N, n-disubstituted alkenamides and phenylalkenamides,... N, n-disubstituted alkenamides and phenylalkenamides,...

C - Chemistry, Metallurgy

07

D

260/552, 260/293

C07D 295/14 (2006.01) C07D 261/18 (2006.01) C07D 295/13 (2006.01)

Patent

CA 1191511

N,N-DISUBSTITUTED ALKENAMIDES AND PHENYLALKENAMIDES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS Abstract: Alkenamides and phenylalkenamides having the formula I Image wherein n represents 0 or 1 R represents C1-4alkyl or the group Image wherein R2 and R3 represent independently C1-4alkyl or together with the nitrogen atom to which they are attached pyrrolidino, piperidino, hexamethyleneimino or morpholino R1 and R4 represent independently halogen C1-4alkyl or C1-4-alkoxy and R5 represents hydrogen or C1-6alkyl, and acid addition salts thereof. The compounds are useful as pharmaceuticals particularly as agents for treating diabetes.

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