N,n-substituted 3-aminopyrrolidine compounds useful as...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/14 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61P 25/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2608184

The present invention provides a pyrrolidine compound of General Formula (1) or a salt thereof, wherein R101 and R102 are each independently a phenyl group or a pyridyl group, the phenyl group or the pyridyl group may have one or more substituents selected from halogen atoms and lower alkyl groups optionally substituted with one or more halogen atoms, etc. The pyrrolidine compound or a salt thereof of the present invention is usable to produce a pharmaceutical preparation having a wider therapeutic spectrum and being capable of exhibiting sufficient therapeutic effects after short-term administration.

La présente invention concerne un dérivé de pyrrolidine de Formule Générale (1) ou un sel de ce dérivé, où R¿101? et R¿102? représentent chacun de façon indépendante un groupement phényle ou un groupement pyridyle, ledit groupement phényle ou groupement pyridyle pouvant comporter un ou plusieurs substituants sélectionnés parmi les atomes d'halogène ou les groupements alkyle inférieurs éventuellement substitués par un ou plusieurs atomes d'halogène, etc. Ledit dérivé de pyrrolidine ou l'un de ses sels selon la présente invention peut être employé pour produire une préparation pharmaceutique de spectre thérapeutique plus étendu et susceptible de présenter des effets thérapeutiques suffisants à court terme après une administration.

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