N,o-sulphated heparosans, process for preparing them and...

Details N,o-sulphated heparosans, process for preparing them and... N,o-sulphated heparosans, process for preparing them and...

C - Chemistry, Metallurgy

12

P

C12P 19/04 (2006.01) C08B 37/00 (2006.01) C08B 37/10 (2006.01) C12N 1/20 (2006.01) C12P 19/44 (2006.01)

Patent

CA 2056878

ABSTRACT N,O-SULPHATED HEPAROSANS, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANOFI The invention relates to new N,O-sulphated heparosans consisting of chains or of a mixture of chains of molecular mass between 1500 and 15,000 Da, characterised by a repeated disaccharide structure of formula I: Image (I) in which: - E represents an acetyl group in 0 to 80% of the disaccharide units of the said N,O-sulphated heparosan, and a sulphate group and possibly a hydrogen atom in the remaining disaccharide units, - G represents a hydrogen atom and a sulphate group, and the pharmaceutically acceptable salts of the said N,O-sulphated heparosans. Medicinal product. Figure: none

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