N-oxides and derivatives of chlorambucil for treating...

C - Chemistry – Metallurgy – 07 – C

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C07C 239/20 (2006.01) A61K 31/195 (2006.01) A61K 31/675 (2006.01) C07C 239/18 (2006.01) C07C 291/04 (2006.01) C07F 9/6584 (2006.01)

Patent

CA 2145585

A compound for treating hypoxic tumor cells is disclosed and having a formula: Image The invention includes a salt and a pharmaceutical formulation including the compound. The invention includes the use of N-oxides and derivatives of chlorambucil for treating hypoxic tumor cells and a method of treating hypoxic tumor cells by administering a pharmaceutical formulation containing N-oxide derivatives.

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