N-oxides of n-phenyl-2-pyrimidine-amine derivatives

Details N-oxides of n-phenyl-2-pyrimidine-amine derivatives N-oxides of n-phenyl-2-pyrimidine-amine derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2474104

The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula (I) in which at least one nitrogen atom carries an oxygen atom to form the corresponding N-oxides, to processes for the preparation thereof, to pharmaceutical compositions comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.

L'invention concerne des dérivés de N-phényl-2-pyrimidine-amine représentés par la formule (I), dans laquelle A est un cycle. Dans ce type de composé, au moins un atome d'azote porte un atome d'oxygène pour former les N-oxydes correspondants. L'invention concerne également des procédés relatifs à l'élaboration des composés en question, des compositions pharmaceutiques renfermant lesdits composés, et l'utilisation de ces composés dans l'élaboration de compositions pharmaceutiques utilisées à des fins thérapeutiques, pour traiter des animaux à sang chaud, y compris les êtres humains.

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