N-phenethylacetamide compounds and process for preparation...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/28 (2006.01) C07D 213/74 (2006.01) C07D 239/46 (2006.01) C07D 239/48 (2006.01) C07D 263/44 (2006.01)

Patent

CA 1110628

ABSTRACT OF THE DISCLOSURE N-phenethylacetamide compounds of the formula: Image wherein X1 represents a lower alkoxy group, X2 represents a hydrogen atom or a lower alkoxy group and R represents a phenyl group, a pyridyl group, a pyrimidinyl group or a benzoyl group, each of which may have one or more substituents selected from a halogen atom, a carbamoyl group, a lower alkoxy group, a sulfamoyl group, an amino group, a lower alkylamino group, a lower alkylthio group, u hydroxy group and a lower alkoxycarbonyl group; the pharmaceutically acceptable acid addition salts and hydrates thereof; as well as the process for preparing such com- pounds and salts and hydrates thereof; the compounds, their salts and their hydrates having a distinct anti-peptic ulcer activity in human and animals.

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