C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/062 (2006.01) A61K 38/05 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2074375
Compounds of the formula (I) in which: R1 is a hydrogen atom, an alkyl, alkoxycarbonyl or optionally substituted phenyl radical; R2 is an alkoxy, optionally substituted cycloalkyloxy, cycloalkyloxy, phenylalkyloxy, polyfluoroalkyloxy, cinnamyloxy, -NR5R6 radical; R3 is a phenylamino radical in which the phenyl nucleus may be substituted, optionally substituted phenyl, naphthyl, indolyl or quinolyl; R4 is a substituted phenyl radical; R5 and R6 are identical or different and represent a hydrogen atom, an alkyl, optionally substituted phenyl, indanyl, cycloalkylalkyl, cycloalkyl, phenylalkyl radical or R5 and R6 together with the nitrogen atom to which they are linked form a heterocycle; their preparation and the medicaments containing them.
BREVET D'INVENTION DERIVES DE N-PHENYL GLYCINAMIDE, LEUR PREPARATION ET LES MEDICAMENT LES CONTENANT RHONE-POULENC RORER S.A. ABREGE Composés de formule : Image (I) dans laquelle - R1 représente un atome d'hydrogène, un radical alkyle, alcoxycarbonyle ou phényle éventuellement substitué - R2 représente un radical alcoxy, cycloalkyloxy éventuellement substitué, cycloalkylalkyloxy, phénylalkyloxy, polyfluoroalkyloxy cinnamyloxy, -NR5R6, - R3 représente un radical phénylamino dont le noyau phényle est éventuellement substitué, phényle éventuellement substitué, naphtyle, indolyle ou quinolyle, - R4 représente un radical phényle substitué - R5 et R6 identiques ou différents représentent un atome d'hydrogène, un radical alkyle, phényle éventuellement substitué, indanyle, cycloalkylalkyle, cycloalkyle, phénylalkyle ou bien R5 et R6 forment ensemble avec l'atome d'azote auxquels ils sont rattachés un hétérocycle, leur préparation et les médicaments les contenant.
Bourzat Jean-Dominique
Capet Marc
Cotrel Claude
Guyon Claude
Manfre Franco
Rhone-Poulenc Rorer S.a.
Robic
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