N-phenyl n-acetamido glycinamides, their preparation and...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/062 (2006.01) A61K 38/05 (2006.01) C07C 205/19 (2006.01) C07C 205/22 (2006.01) C07C 205/37 (2006.01) C07C 205/56 (2006.01) C07C 205/58 (2006.01) C07C 205/60 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2072981

Compounds of formula (I), wherein R1 represents a hydrogen atom or an optionally substitued alkyl, alkoxycarbonyl or phenyl radical; R2 represents a hydrogen atom or an optionally substituted alkyl radical; R3 represents an optionally substituted alkyl, phenylalkyl, indanyl, cycloalkylalkyl or phenyl radical; or R2 and R3 together form a heterocycle with the nitrogen atom to which they are linked; R4 represents an optionally substitued phenyl, naphthyl, indolyl, quinolyl or phenylamino radical of which the phenyl core is optionally substitued. A preparation method and the drugs containing said compounds are also described.

BREVET D'INVENTION N-PHENYL N-ACETAMIDO GLYCINAMIDE LEUR PREPARATION ET LES MEDICAMENTS LES CONTENANT RHONE-POULENC RORER S. A. ABREGE Composés de formule : Image dans laquelle - R1 représente un atome d'hydrogène ou un radical alkyle, alcoxycarbonyle ou phényle éventuellement substitué - R2 représente un atome d'hydrogène ou un radical alkyle éventuellement substitué, - R3 représente un radical alkyle, phénylakyle, indanyle, cycloalkylalkyle ou phényle éventuellement substitué ou bien - R2 et R3 forment ensemble avec l'atome d'azote auquel ils sont rattachés un hétérocycle - R4 représente un radical phényle éventuellement substitué, naphtyle, indolyle, quinolyle ou phénylamino dont le noyau phényle est éventuellement substitué leur préparation et les médicaments les contenant.

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