N-phenyl-piperazine derivatives and methods of prophylaxis...

Details N-phenyl-piperazine derivatives and methods of prophylaxis... N-phenyl-piperazine derivatives and methods of prophylaxis...

C - Chemistry, Metallurgy

07

D

C07D 295/06 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2529750

The present invention relates to certain substituted N-phenyl-piperazine derivatives of Formula: (I) that are modulators of the 5HT2c receptor. Accordingly, compounds of the present invention are useful for the prophylaxis or treatment of 5HT2c receptor associated diseases or disorders, such as, obesity, Alzheimer Disease, erectile dysfunction and related disorders.

L'invention concerne certains dérivés de N-phenyl-piperazine substitués représentés par la formule (I) constituant des modulateurs du récepteur 5HT¿2c?. De ce fait, les composés de l'invention sont utilisés pour la prophylaxie ou le traitement de troubles ou de maladies associés au récepteur 5HT¿2c?, tels que l'obésité, la maladie d'Alzheimer, le dysfonctionnement érectile et des troubles associés.

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