N-phenylalkyl substituted alpha-amino carboxamide...

Details N-phenylalkyl substituted alpha-amino carboxamide... N-phenylalkyl substituted alpha-amino carboxamide...

C - Chemistry, Metallurgy

07

C

167/207, 167/268

C07C 237/06 (2006.01) A61K 31/16 (2006.01) A61K 31/33 (2006.01) C07C 323/60 (2006.01) C07C 323/63 (2006.01) C07D 213/30 (2006.01) C07D 213/56 (2006.01) C07D 307/12 (2006.01) C07D 307/58 (2006.01) C07D 333/16 (2006.01) C07D 333/32 (2006.01)

Patent

CA 2033190

N-phenylalkyl substituted .alpha.-amino carboxamide derivatives of formula (I) Image wherein R is C1-C8 alkyl, C3-C8 cycloalkyl, furyl, thienyl, pyridyl or unsubstituted or substituted phenyl: A is a -(CH2)m- or -(CH2)p-X-(CH2)q-group wherein X is -O-, -S- or -NR4-; R1, R2, R3, R3', R4, n, m, p and q are as herein defined: and each of R5 and R6 is independently hydrogen or C1-C6 alkyl, and the pharmaceutically acceptable salts thereof, are active on the central nervous system and can be used as anti-epileptic, anti-Parkinson, neuroprotective, antidepressant, antispastic and/or hypnotic agents in mammals.

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