C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
167/218, 260/255
C07F 9/6512 (2006.01) A61K 31/675 (2006.01) C07F 9/6561 (2006.01)
Patent
CA 1340856
Disclosed are N-(2-phosphonylmethoxyethyl) and N-(3-hydroxy-2-phosphonylmethoxypropyl) derivatives of pyrimidine and purine bases, easily accessible from such heterocyclic bases and their N-(2-hydroxyethyl) or N-(2,3-dihydroxypropyl) derivatives. Most of the compounds exhibit a marked antiviral activity against DNA-viruses and can be used in therapeutic antiviral compositions.
542404
de Clercq Erik
Holy Antonin
Rosenberg Ivan
Borden Ladner Gervais Llp
de Clercq Erik
Holy Antonin
Institute Of Organic Chemistry And Biochemistry Of The Academy O
Rosenberg Ivan
LandOfFree
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