N-piperidine derivates as ccr3 modulators

Details N-piperidine derivates as ccr3 modulators N-piperidine derivates as ccr3 modulators

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/445 (2006.01) A61K 31/454 (2006.01) A61P 3/04 (2006.01) A61P 25/00 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2558058

Compounds of formula I, processes for preparing such compounds, their use in the treatment of obesity, psychiatric disorders, cognitive disorders, memory disorders, schizophrenia, epilepsy, and related conditions, and neurological disorders such as dementia, multiple sclerosis, Parkinson's disease, Huntington's chorea and Alzheimer's disease and pain related disorders and to pharmaceutical compositions containing them.

La présente invention concerne des composés représentés par la formule I, des procédés permettant de préparer de tels composés, leur utilisation dans le traitement de l'obésité, des troubles psychiatriques, des troubles cognitifs, des troubles de la mémoire, de la schizophrénie, de l'épilepsie et de troubles associés, ainsi que des troubles neurologiques, tels que la démence, la sclérose en plaques, la maladie de Parkinson, la chorée de Huntington et la maladie d'Alzheimer et la douleur associée à ces troubles. Cette invention concerne également des compositions pharmaceutiques contenant de tels composés.

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