N-pyrazole a2a receptor agonists

Details N-pyrazole a2a receptor agonists N-pyrazole a2a receptor agonists

C - Chemistry, Metallurgy

07

H

C07H 19/16 (2006.01) A61K 31/7076 (2006.01) A61K 49/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2377746

2-adenosine N-pyrazole compounds having the following formula: (see formula I) and methods for using the compounds as A2A receptor agonists to stimulate mammalian coronary vasodilation for therapeutic purposes and for purposes of imaging the heart.

L'invention porte sur des composés de 2-adénosine N-pyrazole ayant formule (1) et sur des procédés d'utilisation de ces composés comme agonistes du récepteur A2A permettant de stimuler la vasodilatation coronarienne mammalienne à des fins thérapeutiques et d'imagerie cardiaque.

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