(n)-((s)-2-hydroxy-3-methyl-butyryl-1-(l-alaninyl)-(s)-1-ami...

Details (n)-((s)-2-hydroxy-3-methyl-butyryl-1-(l-alaninyl)-(s)-1-ami... (n)-((s)-2-hydroxy-3-methyl-butyryl-1-(l-alaninyl)-(s)-1-ami...

C - Chemistry, Metallurgy

07

D

C07D 223/00 (2006.01) A61K 31/55 (2006.01) C07D 223/16 (2006.01)

Patent

CA 2425497

The present invention provides crystalline (N)-((S)-2-hydroxy-3-methyl- butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-4,5,6,7-tetrahydro-2H-3- benzazepin-2-one dihydrate, compositions thereof, and methods for using the same, processes for making the same, and processes for making intermediates thereof.

La présente invention concerne des dihydrates (N)-((S)-2-hydroxy-3-méthyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-méthyl-4,5,6,7-tétrahydro-2H-3-benzazépin-2-one cristallins, des compositions correspondantes, des procédés d'utilisation et de production desdits dihydrates et des procédés de production d'intermédiaires correspondants.

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