N.sub.b-quaternary derivatives of ajmaline and isoajmaline,...

Details N.sub.b-quaternary derivatives of ajmaline and isoajmaline,... N.sub.b-quaternary derivatives of ajmaline and isoajmaline,...

C - Chemistry, Metallurgy

07

D

260/241.1

C07D 459/00 (2006.01) C07D 471/22 (2006.01)

Patent

CA 1147329

ABSTRACT OF THE DISCLOSURE New quaternary derivatives of 10-bromoajmaline and 10-bromoisoajmaline are disclosed which exhibit antiarrhythmic and adrenolytic properties and which have the formula I Image (I) wherein R represents a carbon-attached organic group containing 1 to 10 carbon atoms and A- represents and acid anion as well as pharmaceutical formulations thereof and processes and intermediates for their preparation.

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