N-substituted azaheterocyclic compounds

Details N-substituted azaheterocyclic compounds N-substituted azaheterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 409/06 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) C07D 207/08 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2267691

The present invention relates to novel N-substituted azaheterocyclic carboxylic acids of general formula (I) wherein X, Y, Z, R1, R2 and r are as defined in the detailed part of the description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides.

L'invention concerne des acides carboxyliques azahétérocycliques N-substitués nouveaux, représentés par la formule générale (I), dans laquelle X, Y, Z, R?1¿, R?2¿ et r sont tels que définis dans la partie détaillée de la description, ou des sels desdits acides. L'invention concerne également des procédés de fabrication desdits acides, des compositions les contenant et l'utilisation desdits acides dans le traitement clinique d'états douloureux, hyperalgésiques et/ou inflammatoires, dans lesquels des fibres C jouent un rôle pathophysiologique en déclenchant une douleur ou une inflammation neurogènes. L'invention concerne enfin l'utilisation desdits acides dans le traitement d'indications qui sont causées par la sécrétion et la circulation de peptides antagonistes de l'insuline ou qui sont liées.

Affiliated with

Also associated with

Rating

N-substituted azaheterocyclic compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-substituted azaheterocyclic compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-substituted azaheterocyclic compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1460823