N-substituted benzene sulfonamides

Details N-substituted benzene sulfonamides N-substituted benzene sulfonamides

C - Chemistry, Metallurgy

07

D

C07D 223/12 (2006.01) A61K 31/55 (2006.01) A61P 25/28 (2006.01) C07D 207/14 (2006.01) C07D 211/56 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 498/12 (2006.01)

Patent

CA 2544350

Disclosed are N-substituted benzenesulfonamides for use intreating in treating or preventing cognitive disorders, such as Alzheimer~s Disease. Formula (I) In formula (I), R1, R2, R3, R4, R3~, R10 and R11 are described herein. The invention also encompasses pharmaceutical compositions comprising compounds of Formula(I) as well as methods of treating cognitive using compounds of Formula (I).

L'invention concerne des benzènesulfonamides N-substitués pouvant traiter ou prévenir des troubles cognitifs, tels que la maladie d'Alzheimer. On décrit un composé de formule (I) dans laquelle R¿1?, R¿2?, R¿3?, R¿4?, R¿3'?, R¿10? et R¿11? sont tels que définis dans le mémorandum descriptif. L'invention concerne en outre des compositions pharmaceutiques contenant des composés de formule (I), ainsi que des méthodes de traitement de troubles cognitifs utilisant des composés de formule (I).

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