N-substituted benzimidazolyl c-kit inhibitors and...

Details N-substituted benzimidazolyl c-kit inhibitors and... N-substituted benzimidazolyl c-kit inhibitors and...

C - Chemistry, Metallurgy

07

D

C07D 235/06 (2006.01) A61K 31/4184 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01) C07D 405/10 (2006.01) C07D 409/10 (2006.01) C07D 409/14 (2006.01) C07D 413/10 (2006.01) C07D 417/14 (2006.01) C40B 40/04 (2006.01) C40B 50/14 (2006.01)

Patent

CA 2589770

Compounds represented by Formula (I) or a pharmaceutically acceptable salt or N-oxide thereof act as c-kit inhibitors and are useful in the treatment of tumors. Combinatorial libraries composed of compounds represented by Formula (I) or benzimidazole compounds represented by Formula (II) are useful in providing compounds to assay for such therapeutically useful compounds.

L'invention concerne des composés représentés par la formule (I) ou un sel pharmaceutiquement acceptable ou un N-oxyde de ceux-ci, utiles dans le traitement des tumeurs. Des banques combinatoires constituées de composés représentés par la formule (I) ou de composés benzimidazoles représentés par la formule (II): formule (II), sont utiles pour fournir des composés servant à doser ces composés thérapeutiquement utiles.

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