N-substituted glycine derivatives as inhibitors of factor xa

Details N-substituted glycine derivatives as inhibitors of factor xa N-substituted glycine derivatives as inhibitors of factor xa

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01)

Patent

CA 2207373

The present invention discloses peptide aldehydes which are potent inhibitors of factor Xa, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

La présente invention concerne des aldéhydes peptidiques qui sont de puissants inhibiteurs du facteur Xa, leurs sels acceptables sur le plan pharmaceutique, des compositions de ceux-ci acceptables sur le plan pharmaceutique et des procédés pour les utiliser comme agents thérapeutiques chez des mammifères présentant des thromboses anormales.

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