N-substituted glycine derivatives: hydroxylase inhibitors

Details N-substituted glycine derivatives: hydroxylase inhibitors N-substituted glycine derivatives: hydroxylase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 237/24 (2006.01) A61K 31/50 (2006.01) A61P 7/06 (2006.01)

Patent

CA 2675252

The invention described herein relates to certain pyridazinedione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.

L'invention concerne certains dérivés de glycine N-substitués de type pyridazinedione de formule (I) qui sont des antagonistes de prolyl hydroxylases HIF et sont utiles pour le traitement de maladies bénéficiant de l'inhibition de cette enzyme, l'anémie étant un exemple.

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