N-substituted indole derivative

Details N-substituted indole derivative N-substituted indole derivative

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) C07D 209/14 (2006.01) C07D 209/16 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2152160

To provide a compound which strongly and persistently shows a depressor activity and a urination disorder-relieving activity by blocking the .alpha.1-adrenergic receptor. Constitution: An N-substituted indole derivative represented by the following formula: Image wherein R1 represents an alkyl group, or a phenyl group which may be substituted by a halogen atom, an alkyl group or an alkoxy group; R2 represents a phenyl group which may be substituted by one or two substituents selected from a halogen atom, an alkyl group, an alkoxy group and 1-piperidyl group, or a 2-pyridyl group which may be substituted by one or two substituents selected from a halogen atom, an alkyl group and an alkoxy group; and n is an integer of from 2 to 5; and an acid addition salt thereof.

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