N-(substituted phenyl)alkanesulfonamide derivatives

Details N-(substituted phenyl)alkanesulfonamide derivatives N-(substituted phenyl)alkanesulfonamide derivatives

C - Chemistry, Metallurgy

07

D

167/228, 167/267

C07D 401/06 (2006.01) A61K 31/44 (2006.01) C07D 211/14 (2006.01) C07D 211/32 (2006.01) C07D 211/54 (2006.01) C07D 213/38 (2006.01) C07D 213/56 (2006.01)

Patent

CA 1263658

Abstract A novel compound of the general formula is useful to treat arrhythmia. Image (XX) in which R1 is a lower alkyl and W is: (1) Image (2) Image (3) Image X is -S-, -SO- or -SO2-, R2 is hydrogen or -(CH2)n-Y n is an integer of 1 to 5, Y is an aryl, pyridyl or a substituted pyridyl, X' is -CO- or -CH(OH)-, p is an integer of 1 to 4, R12 is hydrogen or a lower alkyl, Y' is -(CH2)m-A, rn is 1 or 2, A is an aryl, a substituted aryl, pyridyl or a substituted pyridyl, R12 and Y may form a 5- or 6-membered ring or a 5- or 6-membered ring having one or more substituents and R22 is hydrogen, a halogen, a lower alkyl, a lower alkoxy or hydroxy.

575436

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