C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) A61K 31/401 (2006.01) A61K 31/4025 (2006.01) A61K 31/404 (2006.01) A61K 31/4155 (2006.01) A61K 31/4178 (2006.01) A61K 31/422 (2006.01) A61K 31/427 (2006.01) A61K 31/428 (2006.01) A61K 31/4439 (2006.01) A61K 31/497 (2006.01) A61P 3/08 (2006.01) C07D 207/16 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2463709
The present invention relates to compounds of formula (I), wherein R1, R2, and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
L'invention concerne des composés représentés par la formule (I), dans laquelle R?1¿, R?2¿ et X sont tels que définis dans le descriptif et dans les revendications, ainsi que des sels pharmaceutiquement acceptables de ceux-ci. Ces composés sont utiles dans le traitement et/ou la prophylaxie de maladies associées à DPP IV, telles que le diabète, plus spécifiquement le diabète sucré non insulino-dépendant, et une tolérance au glucose altérée.
Boehringer Markus
Hunziker Daniel
Kuehne Holger
Loeffler Bernd Michael
Sarabu Ramakanth
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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