N-sulfamoyl-n'-benzopyranpiperidines as inhbitors of...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/10 (2006.01) A61K 31/438 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01) A61P 27/06 (2006.01) A61P 35/00 (2006.01) C07D 491/20 (2006.01)

Patent

CA 2629864

The present invention relates to novel N-sulfamoyl-N'-benzopyranpiperidines of general formula (I) and their physiologically acceptable acid addition salts, to pharmaceutical compositions comprising them, processes for their preparation, and their use for the prophylaxis and/or treatment and/or prevention and/or inhibition of glaucoma, epilepsy, bipolar disorders, migraine, neuropathic pain, obesity, type II diabetes, metabolic syndrome, alcohol dependence, and/or cancer, and its concomitant and/or secondary diseases or conditions.

La présente invention concerne de nouvelles N-sulfamoyl-N'-benzopyranpipéridines de formule générale (I) ainsi que leurs sels d'addition acide de qualité physiologique, des préparations pharmaceutiques les comprenant, des procédés de synthèse de ces composés, et leurs applications dans la prophylaxie et/ou le traitement et/ou la prévention et/ou l'inhibition du glaucome, de l'épilepsie, des troubles bipolaires, de la migraine, de la douleur neuropathique, de l'obésité, du diabète de type II, du syndrome métabolique, de la dépendance à l'alcool et/ou du cancer, ainsi que des maladies et états pathologiques concomitants et/ou secondaires.

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