N-sulfonyl-tetrahydro-[1,3]-dioxepino[5,6-b]azirines,...

Details N-sulfonyl-tetrahydro-[1,3]-dioxepino[5,6-b]azirines,... N-sulfonyl-tetrahydro-[1,3]-dioxepino[5,6-b]azirines,...

C - Chemistry, Metallurgy

07

D

C07D 491/056 (2006.01) A61K 31/395 (2006.01) C07D 491/04 (2006.01) C07D 491/20 (2006.01)

Patent

CA 2115269

2115269 9304067 PCTABS00020 Starting from cis-2-butene-1,4-diol, via the 4,7-dihydro-1,3-dioxepin and trans-6-acylamino-5-chloro-1,3-dioxepans the novel tetrahydro-[1,3]-dioxepino[5,6-b]azirines of formula (VI) were synthesized, and therefrom the novel hypoglycaemically active N-sulfonyl-tetrahydro-[1,3]-dioxepino[5,6-b]azirines of formula (I). The inventive compounds are valuable intermediates in the synthesis of other biologically active substances.

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