C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/08 (2006.01) A61L 15/00 (2006.01) A61L 24/08 (2006.01) A61L 26/00 (2006.01) A61L 27/00 (2006.01) A61L 27/20 (2006.01) A61L 27/26 (2006.01) A61L 29/04 (2006.01) A61L 31/04 (2006.01) A61L 33/00 (2006.01) A61L 33/08 (2006.01)
Patent
CA 2285542
The present invention is directed to novel sulphated compounds of hyaluronic acid and derivatives thereof, optionally salified, wherein the glucosamines are partially N-sulphated or partially N-sulphated and partially or totally O-sulphated in position 6. The compounds of the invention have anticoagulant and antithrombotic activities and are useful in the preparation of pharmaceutical compositions and biomaterials and in the production of coatings for biomedical objects.
L'invention concerne de nouveaux composés sulfatés d'acide hyaluronique et leurs dérivés, ayant éventuellement subi une salification, dans lesquels les glucosamines sont partiellement N-sulfatées ou partiellement N-sulfatées et partiellement ou totalement Q-sulfatées en position 6. Ces composés présentent une activité anticoagulante et antithrombotique et sont utiles à la préparation de compositions pharmaceutiques, ainsi qu'à la fabrication de revêtements d'instruments médicaux.
Callegaro Lanfranco
Renier Davide
Fidia Advanced Biopolymers Srl
Fidia Farmaceutici S.p.a.
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
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