N-terminal fragment of human pro-opiomelanocortin and...

C - Chemistry – Metallurgy – 07 – K

Patent

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167/110, 530/7.1

C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1176162

MCH-2 ABSTRACT OF THE DISCLOSURE There are disclosed the N-terminal fragment of human pro-opiomelanocor-tin, a glycopeptide composed of 76 amino acid residues, and a process for preparing same from human pituitary glands. The glycopeptide is useful in potentiating the effects of ACTH on steroidogenesis, in stimulating the production of aldosterone, as a diagnostic tool, as well as a reagent for determining its presence in biological fluids and tissues by immunochemical means.

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