N-terminal sequencing of proteins and peptides

Details N-terminal sequencing of proteins and peptides N-terminal sequencing of proteins and peptides

G - Physics

01

N

G01N 33/68 (2006.01) C07K 1/12 (2006.01)

Patent

CA 2149217

2149217 9508119 PCTABS00036 An improved method for the N-terminal sequential degradation of proteins and peptides is disclosed. The protein or peptide to be sequenced is reacted with a compound effective to impart a tertiary amine functionality to the thiazolinone derivative of a cleaved terminal amino acid of the peptide.

Procédé amélioré pour la dégradation séquentielle sur la terminaison N de protéines et peptides. La protéine ou le peptide à séquencer est mis en réaction avec un composé qui peut conférer une fonction amine tertiaire au dérivé de thiazolinone d'un acide aminé terminal clivé du peptide.

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