N-terminally chemically modified protein compositions and...

Details N-terminally chemically modified protein compositions and... N-terminally chemically modified protein compositions and...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 38/19 (2006.01) A61K 47/30 (2006.01) A61P 7/00 (2006.01) C07K 1/113 (2006.01)

Patent

CA 2472085

Provided herein are preparations and compositions relating to the attachment of water soluble polymers to proteins. The water soluble polymer can be polytheylene glycol conjugated to the protein via an amino group on the protein, wherein the protein is monopegylated and the polyethylene glycol is conjugated predominantly at the N- terminus of the protein.

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