C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01) C07D 491/048 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2710046
N3-Heteroaryl substituted triazoles and N5-heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.
L'invention concerne des triazoles substitués par N3-hétéroaryle et des triazoles substitués par N5-hétéroaryle et des compositions pharmaceutiques contenant les composés utiles pour l'inhibition de l'activité de la protéine tyrosine kinase réceptrice Axl. Les procédés d'utilisation des composés dans le traitement de maladies ou de conditions associées à l'activité de Axl sont également décrits.
Ding Pingyu
Goff Dane
Heckrodt Thilo
Holland Sacha
Litvak Joane
Gowling Lafleur Henderson Llp
Rigel Pharmaceuticals Inc.
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