N4-phenyl-quinazoline-4-amine derivatives and related...

Details N4-phenyl-quinazoline-4-amine derivatives and related... N4-phenyl-quinazoline-4-amine derivatives and related...

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2632194

This invention provides compounds of Formula (I), wherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.

La présente invention concerne des composés de formule (I), dans laquelle B, G, A, E, R1, R2, R3, m et n sont tels que définis ici, lesquels sont utiles en tant qu'inhibiteurs du récepteur de la tyrosine kinase de type I, et des procédés d'utilisation de ceux-ci dans le traitement de troubles hyperprolifératifs chez des mammifères.

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