Na-k-atpase inhibiting natriuretic substances

Details Na-k-atpase inhibiting natriuretic substances Na-k-atpase inhibiting natriuretic substances

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 38/08 (2006.01) A61K 39/395 (2006.01) C07K 1/14 (2006.01) C07K 4/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/26 (2006.01) G01N 33/567 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2068412

2068412 9204910 PCTABS00011 The invention provides methods for obtaining substantially purified high and low molecular weight Na-K-ATPase inhibitor compounds having natriuretic and vasoconstrictive activity, antibodies reactive with the compounds and methods for their use in diagnostic and therapeutic applications to detect elevated or decreased amounts of the compounds in subjects having diseases associated with the presence or deficiency of these natriuretic compounds.

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