Nact as a target for lifespan expansion and weight reduction

Details Nact as a target for lifespan expansion and weight reduction Nact as a target for lifespan expansion and weight reduction

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 33/00 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2506666

The present invention provides the identification and characterization of a novel transmembrane transporter, a Na+-coupled citrate transporter ("NaCT"). Isolated polynucleotides encoding the transmembrane transporter, the transmembrane transporter polypeptide itself, antibodies thereto, and methods of use, are provided.

L'invention concerne l'identification et la caractérisation d'un nouveau transporteur de transmembrane, à savoir d'un transporteur de citrate couplé à Na?+¿ ("NaCT"). L'invention concerne des polynucléotides isolés codant le transporteur de transmembrane, le polypeptide transporteur de transmembrane lui-même, des anticorps, et leurs procédés d'utilisation.

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