Naive screening method

Details Naive screening method Naive screening method

G - Physics

01

N

G01N 33/53 (2006.01) C07K 1/04 (2006.01) C07K 14/705 (2006.01) C12N 15/10 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2392939

The invention describes a method for isolating, from a naïve polypeptide repertoire which has not been preselected with a specific target ligand, a polypeptide of interest capable of interacting with said specific target ligand, which method comprises direct screening of the naïve polypeptide repertoire with the target ligand in order to identify the polypeptide of interest.

La présente invention concerne un procédé d'isolation, à partir d'un répertoire de polypeptides naïfs n'ayant pas été présélectionnés avec un ligand cible spécifique, d'un polypeptide recherché capable d'interagir avec ledit ligand cible spécifique. Ce procédé consiste à cribler directement le répertoire de polypeptides naïfs avec le ligand cible afin d'identifier le polypeptide recherché.

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