G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/543 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2490765
A composition is disclosed which is capable of being used for detection, comprising an encapsulated noble metal nanocluster. Methods for preparing the encapsulated noble metal nanoclusters, and methods of using the encapsulated noble metal nanoclusters are also disclosed. The noble metal nanoclusters are preferably encapsulated by a dendrimer or a peptide. The encapsulated noble metal nanoclusters have a characteristic spectral emission, wherein said spectral emission is varied by controlling the nature of the encapsulating material, such as by controlling the size of the nanocluster and/or the generation of the dendrimer, and wherein said emission is used to provide information about a biological state.
Cette invention, qui a trait à une composition utilisable pour une détection, renfermant un bloc aux dimensions nanométriques de métal noble encapsulé, concerne également des méthodes d'utilisation de ces blocs. Ces derniers sont, de préférence, encapsulés dans un dendrimère ou un peptide. Ils se caractérisent par leurs propriétés d'émission spectrale, que l'on peut modifier en agissant sur la nature du matériau d'encapsulation, notamment sur la taille du bloc et/ou la préparation du dendrimère. On utilise cette émission pour obtenir des informations sur un état biologique.
Dickson Robert Martin
Zheng Jie
Finlayson & Singlehurst
Georgia Tech Research Corporation
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