Nano-sized particles comprising multi-headed amphiphiles for...

A - Human Necessities – 61 – K

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A61K 9/127 (2006.01) A61K 9/51 (2006.01)

Patent

CA 2761042

Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic compound is selectively cleavable or contains a selectively cleavable group, and at least one biologically active agent, which is both encapsulated within the nano-particle and non-covalently associated thereto.

L'invention porte sur des particules de dimension nanométrique comprenant au moins un composé amphiphile à têtes multiples, dans lequel au moins un groupe de têtes dudit composé amphiphile à têtes multiples est clivable sélectivement ou contient un groupe clivable sélectivement, et au moins un agent actif biologiquement qui est à la fois encapsulé à l'intérieur de la nanoparticule et associé de façon non covalente à celle-ci.

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