Nanocapsule encapsulation system and method

Details Nanocapsule encapsulation system and method Nanocapsule encapsulation system and method

A - Human Necessities

61

K

A61K 9/51 (2006.01) A61K 9/10 (2006.01) A61K 9/107 (2006.01) A61K 31/7088 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) B01J 13/08 (2006.01)

Patent

CA 2400172

The present invention generally relates to nanocapsules and methods of preparing these nanocapsules. The present invention includes a method of forming a surfactant micelle and dispersing the surfactant micelle into an aqueous composition having a hydrophilic polymer to form a stabilized dispersion of surfactant micelles. The method further includes mechanically forming droplets of the stabilized dispersion of surfactant micelles, precipitating the hydrophilic polymer to form precipitated nanocapsules, incubating the nanocapsules to reduce a diameter of the nanocapsules, and filtering or centrifuging the nanocapsules.

La présente invention concerne généralement des nanocapsules et des procédés de préparation de ces nanocapsules. L'invention concerne également un procédé permettant de former une micelle tensio-active et de disperser cette micelle tensio-active dans une composition aqueuse comprenant un polymère hydrophile afin d'obtenir une dispersion stabilisée de micelles tensio-actives. Le procédé de l'invention consiste à former mécaniquement des gouttelettes de la dispersion stabilisée de micelles tensio-actives, à précipiter le polymère hydrophile afin d'obtenir des nanocapsules précipitées, à faire incuber les nanocapsules pour réduire leur diamètre, et à filtrer ou centrifuger les nanocapsules obtenues.

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