Nanofiber structures on asperities for sequestering,...

A - Human Necessities – 61 – M

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A61M 37/00 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 39/08 (2006.01)

Patent

CA 2650197

A device which comprises a substrate which includes a plurality of asperities, such as microneedles, extending from the surface of the substrate, and an electrospun material in contact with the substrate. The electrospun material may comprise a plurality of nanofibers which carry at least one biologically active agent. Such devices are useful as transdermal delivery devices for delivering pharmaceuticals and other biologically active agents.

La présente invention concerne un substrat qui comprend une pluralité d'aspérités, telles des microaiguilles, se prolongeant depuis la surface du substrat et un matériau électrofilé en contact avec le substrat. Le matériau électrofilé peut se composer d'une pluralité de nanofibres portant au moins un agent biologiquement actif. De tels dispositifs se révèlent utiles en tant que dispositifs d'administration transdermique en vue de d'administrer des produits pharmaceutiques et d'autres agents biologiquement actifs.

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