A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/04 (2006.01)
Patent
CA 2674957
The present invention is generally directed to core/shell nanoparticles, wherein such core/shell nanoparticles comprise a nanoparticle core and a nanoshell disposed about the nanoparticle core such that, in the aggregate, they form a core/shell nanoparticle that is operable for use as an imaging agent in X-ray/computed tomography (CT). Typically, such core/shell nanoparticle-based X-ray CT imaging agents further comprise a targeting species for targeting the imaging agent to diseased sites.
La présente invention concerne généralement des nanoparticules à noyau/à enveloppe, ces nanoparticules à noyau/à enveloppe comprenant un noyau de nanoparticule et une enveloppe de nanoparticule disposée autour du noyau de nanoparticule afin que, dans l'agrégat, ils forment une nanoparticule à noyau/à enveloppe qui puisse être utilisée comme un agent de formation d'images pour la tomographie à rayons X/la tomodensitométrie (CT). Généralement, ces agents de formation d'images de tomographie à rayons X basés sur des nanoparticules à noyau/à enveloppe comprennent en outre une espèce de ciblage destinée à cibler l'agent de formation d'images vers des sites atteints.
Axelsson Oskar
Bales Brian
Bonitatibus Peter Jr.
Buckley Paul
Colborn Robert Edgar
Company General Electric
Fetherstonhaugh & Co.
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