Nanoparticle contrast agents for diagnostic imaging

Details Nanoparticle contrast agents for diagnostic imaging Nanoparticle contrast agents for diagnostic imaging

A - Human Necessities

61

K

A61K 49/04 (2006.01) A61K 49/18 (2006.01)

Patent

CA 2748408

Nanoparticles (10) functionalized with at least one zwitterionic moiety, and compositions comprising said nanoparticles are provided. The nanoparticles (10) have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle (10) comprises a core (20), having a core surface (30) essentially free of silica, and a shell (40) attached to the core surface (30). The shell (40) comprises at least one silane- functionalized zwitterionic moiety. Further, methods of making said nanoparticles and methods of their use as diagnostic agents are provided.

La présente invention porte sur des nanoparticules (10) fonctionnalisées avec au moins un fragment zwittérionique et sur des compositions contenant lesdites nanoparticules. Les nanoparticules (10) possèdent des caractéristiques ayant pour résultat une rétention minimale des particules dans le corps par rapport à d'autres nanoparticules. La nanoparticule (10) comprend un noyau (20) possédant une surface de noyau (30) essentiellement exempte de silice et une enveloppe (40) fixée à la surface de noyau (30). L'enveloppe (40) renferme au moins un fragment zwittérionique fonctionnalisé silane. L'invention concerne en outre des procédés de fabrication desdites nanoparticules, ainsi que des procédés destinés à les utiliser en tant qu'agents de diagnostic.

Affiliated with

Also associated with

Rating

Nanoparticle contrast agents for diagnostic imaging does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nanoparticle contrast agents for diagnostic imaging, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nanoparticle contrast agents for diagnostic imaging will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2036540