Nanoparticle imaging system and method

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2455118

An apparatus and method for imaging metallic nanoparticles is provided. Preferably, the invention provides for an apparatus and method for detection of gold colloid particles and for accurate reporting to the operator. The apparatus includes a substrate holder for holding the substrate, a processor and memory device, an imaging module, an illumination module, a power module, an input module, and an output module. The apparatus may have a stationary substrate holder and imaging module which are proximate to one another. The apparatus provided for a compact sized system without the need for complex motorized devices to move the camera across the substrate. Further, the apparatus and method provide for automatic detection of the spots/wells on the substrate, automatic quantification of the spots on the substrate, and automatic interpretation of the spots based on decision statistics.

L'invention concerne un appareil et un procédé destinés à imager des nanoparticules métalliques. De préférence, l'invention concerne un appareil et un procédé destinés à détecter des particules d'or colloïdales et à établir un rapport précis à l'opérateur. L'appareil comprend un support de substrat destiné à supporter le substrat, un dispositif processeur et mémoire, un module d'imagerie, un module d'éclairage, un module de puissance, un module d'entrée et un module de sortie. L'appareil peut comprendre un support de substrat fixe et un module d'imagerie placés à proximité l'un de l'autre. L'appareil de l'invention fournit un système de dimension compacte ne nécessitent pas de dispositifs motorisés complexes aux fins de déplacer la caméra à travers le substrat. En outre, l'appareil et le procédé permettent de détecter de façon automatique des points/puits sur le substrat, de quantifier de façon automatique les points se trouvant sur le substrat, et d'interpréter de façon automatique ces points en fonction de statistiques de décision.

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