A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/48 (2006.01) A61K 9/14 (2006.01) A61K 9/50 (2006.01) A61K 9/51 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2575407
The aim of the invention is to provide biodegradable nanoparticles which ensure a uniform and definable transport of active substances, and to provide an appropriate method for producing these nanoparticles. To these ends, the invention provides that the nanoparticles are essentially comprised of an aqueous gelatin gel. The average diameter of the nanoparticles does not exceed 350 nm, the polydispersity index of the nanoparticles is less than or equal to 0.15, and a gelatin is used as a starting material for the production method whose proportion of gelatin with regard to the total gelatin is no greater than 40 % by weight with a molecular weight less than 65 kDa.
L'invention vise à mettre au point des nanoparticules biodégradables, permettant d'assurer un transport de principe actif, de manière homogène et définissable, ainsi que simultanément un procédé approprié pour produire lesdits nanoparticules. A cet effet, il est prévu que les nanoparticules se composent essentiellement de gel de gélatine aqueux. Le diamètre moyen des nanoparticules s'élève au maximum à 350 nm. L'indice de polydispersivité des nanoparticules est inférieur ou égal à 0,15 et le matériau de départ utilisé pour le processus de production est une gélatine, dont la proportion de gélatine atteint au maximum 40 % en poids, pour un poids moléculaire inférieur à 65 kDa, par rapport à l'ensemble de la gélatine.
Ahlers Michael
Coester Conrad
Zillies Jan
Zwiorek Klaus
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Gelita Ag
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