Nanoparticles comprising a cyclodextrin and a biologically...

Details Nanoparticles comprising a cyclodextrin and a biologically... Nanoparticles comprising a cyclodextrin and a biologically...

A - Human Necessities

61

K

A61K 9/51 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2684560

The nanoparticles comprise a biodegradable polymer, a cyclodextrin or a derivative thereof and a biologically active molecule. Said nanoparticles can associate high quantities of biologically active molecules, in particular, hydrophobic molecules, and release the biologically active molecule by providing sustained and constant plasmatic levels thereof when administered orally or through any other mucosa of the organism.

L'invention concerne des nanoparticules comprenant un polymère biodégradable, une cyclodextrine ou un dérivé de celle-ci, ainsi qu'une molécule biologiquement active. Lesdites nanoparticules peuvent associer des quantités élevées de molécules biologiquement actives, notamment de nature hydrophobe, et libérer la molécule biologiquement active en vue de l'obtention de concentrations plasmatiques soutenues et constantes de cette molécule lors d'une administration par voie orale ou par n'importe quelle autre muqueuse de l'organisme.

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