Nanoparticles comprising a metallic or semiconductor core...

Details Nanoparticles comprising a metallic or semiconductor core... Nanoparticles comprising a metallic or semiconductor core...

A - Human Necessities

61

K

A61K 9/51 (2006.01) A61K 47/48 (2006.01) G01N 33/58 (2006.01) G01N 33/80 (2006.01)

Patent

CA 2424734

Materials and methods for studying and modulating the interaction of carbohydrate-containing moieties with other species are described, in particular, small particles, e.g. clusters of metal or semiconductor atoms, which can be employed as a substrate for immobilising a plurality of ligands comprising carbohydrate groups. These "nanoparticles" can then be used to study carbohydrate mediated interactions, e.g. with other carbohydrates or proteins, and as therapeutics and diagnostic reagents.

L'invention concerne des matériaux et des procédé destinés à l'étude et à la modulation de fractions à teneur en hydrates de carbone avec d'autres espèces, en particulier, de petites particules, par exemple, des grappes d'atomes métalliques ou semi-conducteurs, pouvant être employés comme substrat pour l'immobilisation d'une pluralité de ligands comprenant des groupes hydrates de carbone. Ces <= nanoparticules >= peuvent alors être utilisées pour étudier les interactions exercées par l'intermédiaire d'hydrates de carbone, par exemple avec d'autres hydrates de carbone ou des protéines, et comme réactifs thérapeutiques et de diagnostic.

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