Nanoparticles designed for drug delivery

Details Nanoparticles designed for drug delivery Nanoparticles designed for drug delivery

A - Human Necessities

61

K

A61K 9/51 (2006.01)

Patent

CA 2640557

The present invention is directed to a method of producing nanoparticles by the miniemulsion method, said nanoparticles being made by adding a defined amount of stabilizer to the reaction system. The present invention is further directed to nanoparticles made by this method and their use for the treatment of diseases and conditions, requiring a pharmaceutical agent to cross one or more physiological barriers, in particular the blood-brain barrier.

La présente invention concerne la production de nanoparticules par un procédé de mini-émulsion, lesdites nanoparticules étant obtenues en ajoutant une quantité définie de stabilisant au système de réaction. La présente invention concerne en outre les nanoparticules fabriquées par ce procédé et leur utilisation dans le traitement de maladies et d'états lorsqu'un tel traitement nécessite le franchissement par un agent pharmaceutique d'une ou plusieurs barrières physiologiques, en particulier la barrière hémato-encéphalique.

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