Nanoparticles for nucleic acid delivery

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2706124

The present invention provides chitosan/RNA nanoparticles that are useful as research tools or medicaments. Prefer-ably, the RNA part of the nanoparticle is a siRNA capable of modulating the expression of a target mRNA. The invention also provides methods for the preparation of chitosan/RNA nanoparticles.

La présente invention concerne des nanoparticules à base de chitosane/ARN qui sont utiles en tant qu'outils de recherche ou de médicaments. De préférence, la partie ARN de la nanoparticule est un ARNsi capable de moduler l'expression d'un ARNm cible. L'invention concerne également des procédés de préparation de nanoparticules à base de chitosane/ARN.

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