Nanoparticulate azelnidipine formulations

Details Nanoparticulate azelnidipine formulations Nanoparticulate azelnidipine formulations

A - Human Necessities

61

K

A61K 31/4427 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2612384

The present invention is directed to compositions comprising a nanoparticulate azelnidipine, or a salt or derivative thereof, having improved bioavailability. The nanoparticulate azelnidipine particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the treatment of hypertension and related diseases.

L'invention concerne des compositions comprenant une azelnidipine nanoparticulaire, un sel ou un dérivé de celle-ci, présentant une meilleure biodisponibilité. Les particules de l'azelnidipine nanoparticulaire de la composition présentent une dimension particulaire moyenne réelle inférieure à environ 2000 nm et sont utilisées dans le traitement de l'hypertension et des maladies apparentées.

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